Uncovering the underlying physical mechanisms of biological systems via quantification of landscape and flux |
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| Affiliation: | 1. State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China;2. Department of Chemistry and Physics, Stony Brook University, Stony Brook, NY 11794-3400, USA |
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| Abstract: | In this review, we explore the physical mechanisms of biological processes such as protein folding and recognition,ligand binding, and systems biology, including cell cycle, stem cell, cancer, evolution, ecology, and neural networks. Our approach is based on the landscape and flux theory for nonequilibrium dynamical systems. This theory provides a unifying principle and foundation for investigating the underlying mechanisms and physical quantification of biological systems. |
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| Keywords: | landscape flux |
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