诱发性耳声发射阈同行为反应阈及听觉脑干反应阈间的相关性

本工作以疏波短声作为刺激声在35位受试者(58耳)分别测出诱发性耳声发射(EOAE)、行为反应(BR)及听觉脑干反应(ABR)的阈值.闭值的主要分布范围:EOAE为10-45dB(nHL),占总数的86%;为10-25dB,占88%;ABR为10-35dB,亦占88%.所有受试耳的三种阈值的相关系数r:EOAE-BR为0.415(p<0.002).EOAE-ABR为0.501(p<0.001),ABR-BR为0.702(p<0.001),均呈显著相关.若仅取BR、ABR或EOAE阈值≥25dB的耳作统计,则EOAE-BR间的r只有0.176及0.292;EOAE-ABR的r只有0.310及0.300,无相关(p0.05),而ABR-BR间的r仍有0.533及0.720,(p<0.05),这些结果表明EOAE与听阈之间只有在后者正常或稍升高时才有一定的相关,当听阈上升较多时相关即不存在.EOAE可以作为听力学检查的一种辅助方法,但不能用它推算听阈.

Correlation among thresholds of evoked otoacoustic emissions,behaviour responses and auditory brainstem responses

In 35 adult human subjects (58 ears) thresholds of rarefaction click evokedotoacoustic emissions (EOAE),behaviour responses (BR) and auditory brainstem responses(ABR) were measured and compared, and correlation coefficients among them calculated.The results revealed that 86% of the measured thresholds were in the range from 10 to 45 dB(nHL) for EOAE,88% from 10 to 25 dB for BR,and 88% from 10 to 35 dB for ABR. Thecorrelation coefficients(γ) for the whole threshold samples were 0. 415(p<0.002)for EOAEvs BR, 0. 501 (p<0. 001)for EOAE vs ABR and 0. 702 (p< 0. 001) for ABR vs BR, allindicating highly significant correlation. However, for those ears whose BR, ABR or EOAEthresholds were elevated, equaling or exceeding 25 dB, significant correlation betweenthresholds of EOAE and BR and of EOAE and ABR no more existed (γ range:0. 176 -0. 310,p>0. 05). In contrast, significant correlation between BR and ABR thresholds in thesame conditions still remained (γ:0. 533- 0. 720, p<0.05). The experimental resultsindicate that the correlation between EOAE and hearing thresholds is significant only forsubjects with normal or slightly lost hearing. EOAE is valuable in audiometry only as anaccessory tool.