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Total synthesis of (+/-)-morphine |
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| Authors: | Uchida Kenji Yokoshima Satoshi Kan Toshiyuki Fukuyama Tohru |
| Affiliation: | Graduate School of Pharmaceutical Sciences, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan. |
| Abstract: | [Structure: see text] The morphinan skeleton was effectively synthesized by an intramolecular Mannich-type reaction. Further transformation led to total synthesis of morphine. |
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