Three-component condensation of 3-aminothiophene derivatives with isatines and Meldrum’s acid. Synthesis of 2,5′-dioxo-3′-phenyl-5′,6′-dihydro-4′H-spiro[indoline-3,7′-thieno[3,2-b]pyridine]-2′-carboxylic acids |
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| Authors: | B V Lichitsky R M Belyi A N Komogortsev A A Dudinov M M Krayushkin |
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| Institution: | 1. N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 47 Leninsky prosp., 119991, Moscow, Russian Federation
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| Abstract: | A method for the synthesis of 2,5′-dioxo-3′-phenyl-5′,6′-dihydro-4′H-spiroindoline-3,7′-thieno3,2-b]pyridine]-2′-carboxylic acids was elaborated based on the three-component condensation of 3-aminothiophenes, Meldrum’s acid, and isatines. |
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