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Synthesis of water-soluble lithium,sodium, potassium,and cesium salts of (E)-2-[4-methoxy(3,4-dimethoxy)-benzylideneamino]-2-alkyl(aralkyl)acetic acids
Authors:E A Dikusar  V I Potkin
Institution:1. Institute of Physical Organic Chemistry, National Academy of Sciences of Belarus, ul. Surganova 13, Minsk, 220072, Belarus
Abstract:A convenient method of preparative synthesis of water-soluble lithium, sodium, potassium, and cesium salts of (E)-2-4-methoxy(3,4-dimethoxy)benzylideneamino]-2-alkyl(aralkyl)acetic acids via reaction of anisic or veratric aldehyde with natural amino acids (glycine, L-valine, L-leucine, L-isoleucine or Ltryptophan) in the presence of lithium hydride or carbonates of sodium, potassium, or cesium in boiling methanol was developed.
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