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Stepwise injection photometric determination of ascorbic acid in drugs
Authors:A. V. Bulatov  U. M. Strashnova  A. B. Vishnikin  G. M. Alekseeva  T. D. Sineva  A. L. Moskvin  L. N. Moskvin
Affiliation:1.Department of Chemistry,St. Petersburg State University,St. Petersburg,Russia;2.Dnepropetrovsk National University,Dnepropetrovsk,Ukraine;3.St. Petersburg State Chemical Pharmaceutical Academy,St. Petersburg,Russia
Abstract:A procedure is developed for the photometric determination of ascorbic acid in drug preparations. It is based on the rapid and highly selective reaction of ascorbic acid with a novel reagent, the guanidinium salt of 1-bismuto-11-molybdophosphoric heteropolyacid. The detection limit for ascorbic acid in stepwise injection analysis makes 15 mg/L, and the duration of single analysis, 5 min.
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