Chemistry of N-fluoropyridinium salts |
| |
Authors: | Kiselyov Alexander S |
| |
Institution: | Small Molecule Drug Discovery, Chemical Diversity, 11558 Sorrento Valley Rd., San Diego, CA 92121, USA. |
| |
Abstract: | This tutorial review deals with developments in the chemistry of N-fluoropyridinium salts in the past decade, including both synthetic and mechanistic aspects. Three distinct types of transformations including: i) fluorination reactions, ii) carbenoid behavior and iii) cine-/tele- substitution involving N-fluoropyridinium cation are exemplified. Procedures for fluorination of carbanions and benzenoid aromatics along with hetarylation processes yielding 2- and 4-substituted pyridines are referenced. Several new discoveries in the area, including three-component condensation reactions of in situ generated N-fluoropyridinium fluoride are described. |
| |
Keywords: | |
本文献已被 PubMed 等数据库收录! |
|