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Development of a method for the determination of heavy metals in calcified tissues by inductively coupled plasma-mass spectrometry |
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| Authors: | K M Lee J Appleton M Cooke K Sawicka-Kapusta M Damek |
| Institution: | Oral Biology Unit, School of Dentistry, The University of Liverpool, Liverpool, L69 3BX, England Fax: 0151 706 5809, GB Centre for Chemical Sciences, Royal Holloway, University of London, Egham, Surrey, TW20 0EX, England, GB Department of Animal Ecology, Institute of Environmental Biology, Jagiellonian University, 30-060 Krakow, Poland, PL |
| Abstract: | Calcified tissues are good indicators of exposure to environmental pollution since the mineral phase incorporates heavy metals to which it is exposed during development. Analysis of these specimens is difficult due to the low concentration of the elements of interest compared with the high concentration of the matrix elements. ICP-MS allows rapid multielement determination of samples and a method for the determination of trace elements in calcified tissues is presented with reference to an SRM of Bone Ash (NIST 1400). |
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