Shape-memory and biocompatibility properties of segmented polyurethanes based on poly(L-lactide) |
| |
| Authors: | Peng Ping Wenshou Wang Peibiao Zhang Xuesi Chen Xiabin Jing |
| |
| Affiliation: | (1) State Key Laboratory of Polymer Physics and Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, 130022, China;(2) Graduate University of Chinese Academy of Sciences, Beijing, 100039, China |
| |
| Abstract: | A series of segmented poly(L-lactide)-polyurethanes (PLA-PUs) were synthesized by a two-step method, with oligo-poly(L-lactide) (PLA) as the soft segments and the reaction product of 2,4-toluene diisocyanate (TDI) and ethylene glycol (EG) as the hard segments. The shape-memory properties and biocompatibility of PLA-PUs were examined. The 50% compressed PLA-PUs could recover almost 100% to their original shape within 10°C from the lowest recovery temperature (22°C–37°C). In the recovery process the PLA-PU showed a maximum contracting stress in the range of 1.5–4 MPa. Cell incubation experiments show that PLA-PU has biocompatibility comparable to that of pure PLA. Therefore, this kind of polyurethane can be used for implanted medical devices with shape memory requirements. __________ Translated from Chemical Journal of Chinese Universities, 2007, 28(2): 371–375 [译自: 高等学校化学学报] |
| |
| Keywords: | polyurethane poly(L-lactide) shape memory biocompatibility |
| 本文献已被 万方数据 SpringerLink 等数据库收录！ |
|
