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| 六味地黄丸指纹图谱的近红外光谱分析方法的建立 | |
| 作者姓名： | Chen B Li JH Zang P Yu YB Tian RH Yan YC Chi YM Zhang LD Yan YL |
| 作者单位： | 1. 中国航天员科研训练中心,北京,100094;北京同仁堂科技发展股份有限公司,北京,100079 2. 中国农业大学信电学院,北京,100083 3. 中国航天员科研训练中心,北京,100094 4. 北京同仁堂科技发展股份有限公司,北京,100079 |
| 摘 要： | 建立了一种近红外光谱测定六味地黄丸指纹图谱的方法。应用毛细管电泳法建立六味地黄丸指纹图谱,计算其相似度,同时测定其近红外光谱,建立六味地黄丸指纹图谱相似度与近红外光谱之间的数学模型。通过对模型的优化,建模集样品的相关系数(r)、校正标准差和平均相对误差分别为0.9046,0.058和6.12%,表明六味地黄丸指纹图谱相似度实测值与预测值之间有较好的线性关系。研究结果表明以基于指纹图谱的近红外光谱法用于六味地黄丸的质量控制具有可行性。 |
| 关 键 词： | 近红外光谱 指纹图谱 相似度 六味地黄丸 |
Analysis method of the fingerprint of LiuWei DiHuang pills by near infrared spectroscopy |
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| Chen B,Li JH,Zang P,Yu YB,Tian RH,Yan YC,Chi YM,Zhang LD,Yan YL.Analysis method of the fingerprint of LiuWei DiHuang pills by near infrared spectroscopy[J].Spectroscopy and Spectral Analysis,2010,30(8):2124-2128. | |
| Authors: | Chen Bin Li Jun-hui Zang Peng Yu Yan-bo Tian Rui-hua Yan Yong-chao Chi Yu-ming Zhang Lu-da Yan Yan-lu |
| Institution: | China Astronaut Research and Training Center, Beijing 100094, China. chenb12@yahoo.com.cn |
| Abstract: | The purpose of the present paper is to establish a method of the fingerprint of LiuWei DiHuang pills by the near infrared spectroscopy. First, the authors established the fingerprint of LiuWei DiHuang pills by high performance capillary electrophoresis (HPCE), and calculated its similarity. At the same time, the authors scanned its near infrared spectrogram. Then the authors established the mathematical model between the similarity of fingerprint and the near infrared spectrogram. Through the optimization of the model, the correlation(r), calibration standard deviation and the average relative error of the modeling set were 0.9046, 0.058 and 6.12%, respectively. It proved that the linearity between calculated and forecast of fingerprint was clear. The results showed that the method of the fingerprint of LiuWei DiHuang pills by the near infrared spectroscopy was feasible. |
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| 本文献已被 CNKI 万方数据 PubMed 等数据库收录！ | |