An iterative image reconstruction algorithm combined with forward and backward diffusion filtering for in‐line X‐ray phase‐contrast computed tomography |
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Authors: | Yuqing Zhao Mengyu Sun Dongjiang Ji Changhong Cong Wenjuan Lv Qi Zhao Lili Qin Jianbo Jian Xiaodong Chen Chunhong Hu |
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Institution: | 1. College of Biomedical Engineering, Tianjin Medical University, Tianjin300070, People's Republic of China;2. The School of Science, Tianjin University of Technology and Education, Tianjin300222, People's Republic of China;3. The Dental Hospital of Tianjin Medical University, Tianjin300070, People's Republic of China;4. Radiation Oncology Department, Tianjin Medical University General Hospital, Tianjin300070, People's Republic of China;5. Key Laboratory of Opto-electronic Information Technology, Ministry of Education (Tianjin University), Tianjin300072, People's Republic of China |
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Abstract: | In‐line X‐ray phase‐contrast computed tomography (IL‐PCCT) can reveal fine inner structures for low‐Z materials (e.g. biological soft tissues), and shows high potential to become clinically applicable. Typically, IL‐PCCT utilizes filtered back‐projection (FBP) as the standard reconstruction algorithm. However, the FBP algorithm requires a large amount of projection data, and subsequently a large radiation dose is needed to reconstruct a high‐quality image, which hampers its clinical application in IL‐PCCT. In this study, an iterative reconstruction algorithm for IL‐PCCT was proposed by combining the simultaneous algebraic reconstruction technique (SART) with eight‐neighbour forward and backward (FAB8) diffusion filtering, and the reconstruction was performed using the Shepp–Logan phantom simulation and a real synchrotron IL‐PCCT experiment. The results showed that the proposed algorithm was able to produce high‐quality computed tomography images from few‐view projections while improving the convergence rate of the computed tomography reconstruction, indicating that the proposed algorithm is an effective method of dose reduction for IL‐PCCT. |
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Keywords: | in‐line X‐ray phase‐contrast computed tomography simultaneous algebraic reconstruction technique forward and backward diffusion filtering few‐view projections |
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