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A new friedelane triterpenoid and saponin with moderate antimicrobial activity from the stems of Drypetes laciniata |
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| Authors: | Simone Veronique Fannanga Victor Kueteb Celine Mbazoa Djamaa Marlise Diane J.Dongfack Jean Duplex Wansid Franois Tillequinc Elisabeth Seguine Elizabeth Chossone Jean W ji a Laboratoire de Synthese et de Produits Naturels Departement de Chimie Organique de I'Universite de Yaounde- Faculte des Sciences P.O.Box Yaounde Cameroon b |
| Affiliation: | Department of Biochemistry,University of Dschang,Faculty of Science,P.O.Box 67 Dschang,Cameroon c Laboratoire de Pharmacognosie de l’Universite Paris Descartes,UMR/CNRS No.8638,Faculte des Sciences Biologiques et Pharmaceutiques, 4-Avenue de l’Observatoire,75006 Paris,France d Department of Chemistry,University of Douala,Faculty of Science,P.O.Box 24157 Douala,Cameroon e Laboratoire de Pharmacognosie,UFR de Medecine Pharmacie Rouen,22-Bld Gambetta,76183 Rouen Cedex 1,France |
| Abstract: | A new friedelane-type triterpene named 3β-hydroxyfriedelane-7,12,22-trione, as well as nine known compounds were isolated from the whole stems of Drypetes laciniata Hutch. (Euphorbiaceae). Their structures were established on the basis of spectroscopic methods. The new triterpene derivative and a known saponin were tested for antimicrobial and antifungal activities and they appeared to be moderate active. |
| Keywords: | Drypetes laciniata Euphorbiaceae Stem Friedelane-type triterpenoid Antimicrobial activity |
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