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Influence of membrane surface properties on the growth of neuronal cells isolated from hippocampus
Authors:Loredana De Bartolo  Maria Rende  Sabrina Morelli  Giuseppina Giusi  Simona Salerno  Antonella Piscioneri  Amalia Gordano  Anna Di Vito  Marcello Canonaco  Enrico Drioli
Institution:1. Institute on Membrane Technology, National Research Council of Italy, ITM-CNR, via P. Bucci Cubo 17/C, Rende (CS), Italy;2. Department of Chemical Engineering and Materials University of Calabria, via P. Bucci, Rende (CS), Italy;3. Comparative Neuroanatomy Laboratory, Department of Ecology, University of Calabria, via P. Bucci, 87030 Rende (CS), Italy;4. Department of Cell Biology, University of Calabria, via P. Bucci, 87030 Rende (CS), Italy
Abstract:Membranes have become of great interest for tissue engineering application, since they offer the advantage of developing neuronal tissue that may be used in implantable or in vitro hybrid systems for the simulation of brain function. The behaviour of neurons isolated from the hippocampus on membranes with different surface properties was investigated.
Keywords:Hippocampal neurons  Membranes  Roughness  Morphology  BDNF secretion
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