Copper-catalyzed synthesis of primary arylamines from aryl halides and 2,2,2-trifluoroacetamide |
| |
Authors: | Chuan-Zhou Tao Yao Fu Qing-Xiang Guo |
| |
Affiliation: | a Department of Chemistry, University of Science and Technology of China, Hefei 230026, China b Department of Chemistry, Tsinghua University, Beijing 100084, China |
| |
Abstract: | A catalytic method was developed to synthesize primary arylamines from the corresponding aryl bromides and iodides under mild conditions (yields = 80-99%). Crystalline 2,2,2-trifluoroacetamide was used as ammonia surrogate and CuI/N,N′-dimethyl ethylenediamine was used as catalyst to achieve the C-N cross-coupling. |
| |
Keywords: | Copper catalysis Ammonia surrogate Cross coupling Primary arylamines |
本文献已被 ScienceDirect 等数据库收录! |
|