A pyridoxal-based chemosensor for visual detection of copper ion and its application in bioimaging |
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| Authors: | Cai-Xia Yin, Li-Jun Qu, Fang-Jun Huo |
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| Affiliation: | a Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Institute of Molecular Science, Shanxi University, Taiyuan 030006, China;b Research Institute of Applied Chemistry, Shanxi University, Taiyuan 030006, China |
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| Abstract: | A pyridoxal-based chemosensor was synthesized by reacting hydrazine hydrate and pyridoxal hydrochloride in ethanol and characterized by NMR and ESI-MS. The optical properties of the compound were investigated in a methanol: HEPES solution. The compound displayed selectivity for Cu2+, as evidenced by a colorless to yellow color change, which was characterized using UV-vis spectroscopy. The fluorescence of the compound can be quenched only by Cu2+, accompanying by a color change from blue to colorless. Furthermore, it can be used in bioimaging. |
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| Keywords: | Pyridoxal-based Copper ion Chemosensor Bioimaging |
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