Synthesen neuer Chinolon-Chemotherapeutika, 1. Mitt.: Pyridochinoline und Pyridophenanthroline als “lin-benzo-Nalidixinsäure”-Derivate |
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| Authors: | U. Jordis F. Sauter M. Rudolf Gan Cai |
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| Affiliation: | (1) Institut für Organische Chemie, Technische Universität Wien, A-1060 Wien, Österreich;(2) South China Institute of Technology, Guangzhou (Canton), The People's Republic of China |
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| Abstract: | Expansion of nalidixic acid (NA) has been accomplished by linear insertion of a benzo-ring between the two pyrido moieties. The resulting compounds exhibit antibacterial activity comparable toNA and are highly fluorescent. The regioselective hydrogenation of 1,7-phenanthrolines was studied. |
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| Keywords: | lin-Benzo-analogs Quinolones Pyrido[3,2-g]quinoline [1H,7H]Pyrido[3,2,1-gh][1,7]phenanthroline [1H,7H]Pyrido[1,2,3-de][4,7]phenanthroline Regioselective hydrogenation of [1,7]phenanthrolines Fluorescence |
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