Cardiac Metastatic Melanoma Investigated by Magnetic Resonance Imaging |
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| Institution: | 2. Stroke Service, Department of Neurosciences, Leeds Teaching Hospitals NHS Trust and Medical School, University of Leeds, Leeds, UK;3. University of Birmingham Institute of Cardiovascular Sciences, City Hospital, Birmingham, UK;4. Department of Medicine, Ioannina University Hospital, School of Medicine, University of Ioannina, Ioannina, Greece;6. Department of Clinical Therapeutics, Medical School of Athens, Alexandra Hospital, Athens, Greece;5. Department of Neurology, Eginition Hospital, University of Athens Medical School, Athens, Greece;2. Biostatistic Department, School of Medicine, Ege University, İzmir, Turkey;1. Department of Radiology, Massachusetts General Hospital, Boston, Massachusetts;2. Department of Radiology, Massachusetts General Hospital, 55 Fruit St, WAC 240, Boston, Massachusetts;3. Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Boston, Massachusetts;1. Department of Radiology, Chiba University Hospital, 1-8-1 Inohana, Chuo-ku, Chiba, Chiba 260-8677, Japan;2. Division of Health Sciences, Graduate School of Medical Sciences, Kanazawa University, 5-11-80 Kodatsuno, Kanazawa, Ishikawa 920-0942, Japan;3. Diagnostic Radiology and Radiation Oncology, Graduate School of Medicine, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba, Chiba 260-8670, Japan;4. Department of Pediatrics, Graduate School of Medicine, Chiba University, 1-8-1, Inohana, Chuo-ku, Chiba, Chiba 260-8670, Japan;1. Memorial Sloan Kettering Cancer Center, Department of Radiology, New York, NY, United States of America;2. Weill-Cornell Medical Center, New York, NY, United States of America |
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| Abstract: | There is a high rate of cardiac involvement in malignant melanoma (MM), but such cardiac metastases are usually diagnosed late. This report describes four cases with different clinical presentations of MM cardiac involvement that were investigated by magnetic resonance imaging (MRI). The MM cardiac involvement was asymptomatic in one case, detected because of a superior vena cava syndrome in a second, and because a tamponade in the remaining two cases. MRI permitted the diagnosis of cardiac metastases of MM, which was not made by echocardiography in one case. By precisely detecting the extent of the tumors, MRI was a great help in management, especially when an isolated cardiac metastasis was suitable for surgical ablation (two cases). Because both clinical signs and transthoracic echocardiogram are not very sensitive for diagnosing MM myocardial involvement, MRI can help provide such a diagnosis and ensure better treatment-monitored decisions. |
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