Molecularly Imprinted Silica-Coated CdTe Quantum Dots for Fluorometric Determination of Trace Chloramphenicol |
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| Authors: | Xiaoxiao Chen Yang Liu Pu Li Yichen Xing Chaobiao Huang |
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| Institution: | 1.College of Chemistry and Life Science, Zhejiang Normal University, Jinhua 321004, China; (X.C.); (Y.L.); (P.L.); (Y.X.);2.Xingzhi College, Zhejiang Normal University, Jinhua 321004, China |
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| Abstract: | A dual recognition system with a fluorescence quenching of quantum dots (QDs) and specific recognition of molecularly imprinted polymer (MIP) for the detection of chloramphenicol (CAP) was constructed. MIP@SiO2@QDs was prepared by reverse microemulsion method with 3-aminopropyltriethoxysilane (APTS), tetraethyl orthosilicate (TEOS) and QDs being used as the functional monomer, cross-linker and signal sources, respectively. MIP can specifically recognize CAP, and the fluorescence of QDs can be quenched by CAP due to the photo-induced electron transfer reaction between CAP and QDs. Thus, a method for the trace detection of CAP based on MIP@SiO2@QDs fluorescence quenching was established. The fluorescence quenching efficiency of MIP@SiO2@QDs displayed a desirable linear response to the concentration of CAP in the range of 1.00~4.00 × 102 μmol × L−1, and the limit of detection was 0.35 μmol × L−1 (3σ, n = 9). Importantly, MIP@SiO2@QDs presented good detection selectivity owing to specific recognition for CAP, and was successfully applied to quantify CAP in lake water with the recovery ranging 102.0~104.0%, suggesting this method has the promising potential for the on-site detection of CAP in environmental waters. |
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| Keywords: | molecular imprinting chloramphenicol quantum dots fluorescence quenching |
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