| A New Sesquiterpene from Transformation of Curdione by Cell Suspension Culture of Platycodon Grandiflorum |
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| 作者姓名： | Xiao Chi MA Li Jun WU De An GUO |
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| 作者单位： | [1]The State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100083 [2]School of Traditional Chinese Medicines, Shenyang Pharmaceutical University, Shengyang 110016 |
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| 基金项目： | We thank the National 0utstanding Youth Trans-Century Training Program Foundation financial support. Foundation by NNSF of China （39925040） and for the Talents by the Ministry of Education for |
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| 摘 要： | Curcuma aromatica (Family Zingiberaceae) is an important medicinal plant and its rhizome has been used as a traditional Chinese medicine possessing activities of anticancer, antioxidation and bile secretion promotion. Curdione, compound 1, with a germacrane skeleton is one of its major active constituents. Recently, curdione was reported to exhibit hepatoprotective activity 1, 2. In an endeavor to find new chemical entities, we examined the plant cell suspension cultures of Platycodon grandi…
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| 关 键 词： | 倍半萜烯 悬浮液 植物药材 根茎 药物 抗氧化作用 |
| 收稿时间： | 2005-03-10 |
A New Sesquiterpene from Transformation of Curdione by Cell Suspension Culture of Platycodon Grandiflorum |
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| Xiao Chi MA Li Jun WU De An GUO.A New Sesquiterpene from Transformation of Curdione by Cell Suspension Culture of Platycodon Grandiflorum[J].Chinese Chemical Letters,2005,16(11):1487-1488. |
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| Authors: | Xiao;Chi;MA;Li;Jun;WU;De;An;GUO |
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| Abstract: | A new sesquiterpene was isolated from transformation of curdione by cell suspension culture of Platycodon grandiflorum. The structure of the new compound was elucidated on the basis of spectral methods including 2D NMR. |
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| Keywords: | Platycodon grandiflorum biotransformation curdione sesquiterpene |
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