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Tosic Acid-on-Silica Gel: A Cheap and Eco-friendly Catalyst for a Convenient One-pot Synthesis of Substituted Benzimidazoles
Authors:Manas Chakrabarty  Ratna Mukherjee  Sulakshana Karmakar  Yoshihiro Harigaya
Institution:(1) Department of Chemistry, Bose Institute, Kolkata, India;(2) Department of Pharmaceutical Sciences, Kitasato University, Tokyo, Japan
Abstract:Summary. 2-Substituted and 1,2-disubstited benzimidazoles were prepared efficiently from o-phenylenediamines and aryl aldehydes using p-toluenesulphonic acid (5 mol%)-on-silica gel as a cheap and environmentally benign catalyst.
Keywords:, Benzimidazoles, Synthesis, o-Phenylenediamines, Aryl aldehydes, Tosic acid-on-silica gel,
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