Facile and efficient synthesis of carbohybrids as stereodivergent druglike small molecules |
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Authors: | Sagar Ram Park Seung Bum |
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Institution: | Department of Chemistry, Seoul National University, Seoul 151-747 Korea. |
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Abstract: | A facile and efficient one-pot synthesis of acyclic polyols fused with pyrazolo1,5-a]pyrimidines and 1,2,4-triazolo1,5-a]pyrimidines as novel carbohybrids with regioselectivity was achieved through the condensation of 2-C-formyl glycals with 3-aminopyrazoles and 3-amino-1,2,4-triazoles in excellent yields under the microwave irradiation. |
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