| Synthesis and Novel Properties of Alkyl Thiophosphoramidate Derivatives of Nucleosides |
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| 引用本文： | 苗志伟,付华,涂光忠,刘海,韩波,赵玉芬. Synthesis and Novel Properties of Alkyl Thiophosphoramidate Derivatives of Nucleosides[J]. 中国化学, 2002, 0(5) |
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| 作者姓名： | 苗志伟 付华 涂光忠 刘海 韩波 赵玉芬 |
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| 作者单位： | MIAO，Zhi Wei FU，Hua a TU，Guang Zhong b LIU Hai a HAN，Bo a ZHAO，Yu Fen ，a a Key Laboratory of Bioorganic Phosphorus Chemistry，Ministry of Education，Department of Chemistry，School |
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| 基金项目： | ProjectsupportedbytheNationalNaturalScienceFoundationofChina (Nos .2 990 2 0 0 3and 39870 4 15 ) ,theMinistryofScienceandTechnology ,theChineseMinistryofEducationandDoctorCandidateInnovationFoundationinTsinghuaUniversity (No .0 92 4 30 30 5 ) |
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| 摘 要： | Ｉｎｔｒｕｄｕｃｔｉｏｎ Ｔｈｅｄｅｖｅｌｏｐｍｅｎｔｏｆｎｕｃｌｅｏｓｉｄｅｐｒｏｄｒｕｇｓｃａｐａｂｌｅｏｆｕｎｄｅｒｇｏｉｎｇｉｎｔｒａｃｅｌｌｕｌａｒａｃｔｉｖａｔｉｏｎｔｏｔｈｅｃｏｒｒｅｓｐｏｎｄｉｎｇｎｕｃｌｅｏｔｉｄｅｈａｓｂｅｃｏｍｅａｎａｒｅａｏｆｉｎｔｅｎｓｅｉｎｔｅｒｅｓｔ.1Ｓｅｖｅｒ ａｌｐｕｒｉｎｅａｎｄｐｙｒｉｍｉｄｉｎｅｂａｓｅｓａｎｄｎｕｃｌｅｏｓｉｄｅａｎａｌｏｇｓａｒｅｉｍｐｏｒｔａｎｔｗｅａｐｏｎｓｉｎｔｈｅａｎｔｉｃａｎｃｅｒａｎｄａｎｔｉｖｉｒａｌｃ…
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Synthesis and Novel Properties of Alkyl Thiophosphoramidate Derivatives of Nucleosides |
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| Abstract: | |
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| Keywords: | synthesis alkyl thiophosphoramidate nucleoside analogue hydrolysis reaction mechanism |
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