Synthesis of (+/-)-trans- or cis-(5-aminomethyltetrahydrofuranyl)imidazole by Mitsunobu cyclization: synthetic studies toward novel histamine H3 or H4-ligands |
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| Authors: | Harusawa Shinya Araki Lisa Imazu Tomonari Ohishi Hirofumi Sakamoto Yasuhiko Kurihara Takushi |
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| Institution: | Osaka University of Pharmaceutical Sciences, Tatatsuki, Japan. |
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| Abstract: | The (+/-)-trans- or cis-4(5)-(5-aminomethyltetrahydrofuranyl)imidazole 1 and 2] were synthesized by the Mitsunobu cyclization, starting from L-glutamic acid. |
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