| Synthesis of Hydroxystilbene Derivatives and their Antioxidant Activity by DPPH Method |
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| 引用本文： | LI Yue-qing SONG Qi-ling CHEN Ping-ping ZHAO Wei-jie WANG Shi-sheng. Synthesis of Hydroxystilbene Derivatives and their Antioxidant Activity by DPPH Method[J]. 高等学校化学研究, 2006, 22(6): 742-746. DOI: 10.1016/S1005-9040(06)60202-X |
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| 作者姓名： | LI Yue-qing SONG Qi-ling CHEN Ping-ping ZHAO Wei-jie WANG Shi-sheng |
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| 作者单位： | LI Yue-qing，SONG Qi-ling，CHEN Ping-ping，ZHAO Wei-jie {**} and WANG Shi-sheng State Key Laboratory of Fine Chemicals，Dalian University of Technology，Dalian 116012，P. R. China |
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| 摘 要： | IntroductionThe increasing interest in the research on antioxi-dants is attributed to the availability of vastevidence re-garding the importance of reactive oxygen/nitrogen spe-cies(ROS/RON) in the processes of aging and patho-genesis. It has been suggest…
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| 关 键 词： | 多羟芪 抗氧化剂活性 1 1-联苯-2-苦味酰基自由基 结构分析 药物分析 |
| 文章编号： | 1005-9040（2006）-06-742-05 |
| 收稿时间： | 2005-11-23 |
Synthesis of Hydroxystilbene Derivatives and their Antioxidant Activity by DPPH Method |
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| Yue-qing LI, Qi-ling SONG, Ping-ping CHEN, Wei-jie ZHAO,Shi-sheng WANG. Synthesis of Hydroxystilbene Derivatives and their Antioxidant Activity by DPPH Method[J]. Chemical Research in Chinese University, 2006, 22(6): 742-746. DOI: 10.1016/S1005-9040(06)60202-X |
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| Authors: | Yue-qing LI Qi-ling SONG Ping-ping CHEN Wei-jie ZHAO Shi-sheng WANG |
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| Affiliation: | aState Key Laboratory of Fine Chemicals, Dalian University of Technology, Dalian 116012, P. R. China |
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| Abstract: | Five hydroxystilbene derivatives were synthesized and their structures were determined using high-resolution mass spectrometry, {} 1H NMR, and IR. In this study, the antioxidant activities of eight hydroxystilbenes(five synthesized hydroxystilbene derivatives and three other compounds) were evaluated with the free radical scavenging model {1,1-}diphenyl-2-picrylhydrazyl. It was observed that there exists a very significant linear relationship between the reciprocal of the EC_ 50 value of each of the compounds and the maximum wavelength of the ultraviolet absorption peaks. It is believed that this result will be helpful for the further synthesis of such antioxidants. |
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| Keywords: | Polyhydroxystilbene Antioxidant activity 1 1-Diphenyl-2-picrylhydrazyl(DPPH) |
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