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Liquid Chromatographic Resolution of Racemic 2-Phenyl-1,1-cyclo- propanedicarbonitrile and its Analogues on Chiral Stationary Phase
Authors:You Cheng LIU  Xin Zhu LI  Jing LI
Abstract:Excellent resolution of racemic 2-phenyl-1.1-cyclopropanedicarbonitrile and its nine analogues was accomplished using 100-5CHl-TBB chiral stationary phase under normal-phase HPLC conditions. The influence of mobile phase and the optimum conditions for the resolution of optically active enantiomers were investigated.
Keywords:HPLC   chiral stationary phase. 2-phenyl-1.1-cyclopropanedicarbonitrile (PCN). chromatographic resolution.
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