Microwave-assisted synthesis of new polysubstituted dienaminoesters and their cyclization to 3-bromo-2(1H)-pyridinones |
| |
| Authors: | Adams Jeff Hardin Alison Vounatsos Filisaty |
| |
| Affiliation: | Chemistry Process Research and Development, Custom Synthesis Laboratory, Amgen Inc., Thousand Oaks, California 91320, USA. |
| |
| Abstract: | A microwave-assisted, telescoped synthesis, involving a Michael-type addition followed by intramolecular cyclization, provides an effective entry to the polysubstituted 3-bromo-2(1H)-pyridinone core. |
| |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ |
|
