Structure determination of lepidopteran c,self-defence substance produced by silkworm (bombyx mori) |
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| Affiliation: | 1. Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, Shanghai 200241, China;2. Center for Cancer and Stem Cell Biology, Institute of Biosciences and Technology, Texas A&M University Health Science Center, Houston, TX 77030, USA |
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| Abstract: | Lepidopteran C is a minor component in a group of lepidopterans which are self-defence substances produced in haemolymph of silkworm. Its structure was determined by the Edman degradation of the whole molecule as well as the fragments obtained by digestion of Staphylococcus aureus V8 protease, proline specific endopeptidase, and trypsin. Although lepidopteran C is similar to A in amino acid sequence, 11 amino acids of A are substituted in the sequence of C. |
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