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Direct fluorination of substituted pyridines
Affiliation:1. Fuel Chemistry Division, Bhabha Atomic Research Centre, Mumbai 400085, India;2. Theoretical Chemistry Section, Bhabha Atomic Research Centre, Mumbai 400085, India;3. Department of Chemistry, University of Reading, P.O. Box 224, Whiteknights, Reading RG6 6AD, UK;1. School of Chemistry and Materials Engineering, Huizhou University, Huizhou 516007, China;2. College of Chemistry and Materials Science, Jinan University, Guangzhou 510632, China;1. Department of Chemistry and Center of Advanced Studies, Panjab University, Chandigarh 160014, India;2. Department of Microbiology, Panjab University, Chandigarh 160014, India;3. Department of Chemical and Pharmaceutical Sciences and Center for Structural Diffractometry, University of Ferrara, via Fossato di Mortara 17-27, 1-44121 Ferrara, Italy;1. Department of Chemistry, Innovative Drug Research Center, Shanghai University, Shanghai, 200444, PR China;2. Qianweichang College, Shanghai University, Shanghai, 200444, PR China;3. Laboratory for Microstructures, Instrumental Analysis and Research Center of Shanghai University, Shanghai, 200444, PR China;4. State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai, 200032, PR China;5. Key Laboratory of Organofluorine Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai, 200032, PR China
Abstract:The direct fluorination of pyridines bearing alkyl, halogen, ester, or ketone functions has been employed to prepare the corresponding 2-fluoro-substituted pyridines.
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