Electrochemical behavior of ellipticine derivatives: Part I. Oxidation of 9-hydroxy-ellipticine |
| |
| Authors: | J. Moiroux A.M. Armbruster |
| |
| Affiliation: | Laboratoire de Chimie Analytique (Prof. M.B. Fleury), Université René Descartes (Paris V), Faculté des Sciences Pharmaceutiques et Biologiques, 4 Avenue de l''Observatoire, 75270 Paris Cedex 05 (France);Laboratoire de Biochimie et Enzymologie, L.A. 147 du C.N.R.S., Groupe 140 I.N.S.E.R.M., Institut Gustave Roussy, 94800 Villejuif (France) |
| |
| Abstract: | The electrochemical one-electron oxidation of 9-hydroxy-ellipticinium cations at a platinum electrode has been examined with particular attention to the thermodynamic redox potential and to the dimerization rate of the radical species produced. Both the reactant and the product of the electrochemical reaction are strongly adsorbed at the solution/electrode interface. The initial step of the anodic process is a reversible electron transfer accompanied by a fast deprotonation; E0′=900?53 pH mV vs. NHE. The resulting neutral radical dimerizes, the rate constant of the surface dimerization being ca. 2.5×109 mol?1 cm2 s?1. |
| |
| Keywords: | To whom all correspondence should be addressed. |
| 本文献已被 ScienceDirect 等数据库收录！ |
