Synthesis of Novel Chiral C
2-symmetric Diaza-18-crown-6 Ether Derivatives and their Enantioselective Recognition of Amino Acid Derivatives |
| |
| Authors: | Y?lmaz Turgut Nadir Demirel Halil Ho?gören |
| |
| Institution: | (1) Faculty of Science, Department of Chemistry, University of Dicle, 21280 Diyarbakır, Turkey |
| |
| Abstract: | New chiral diaza-18-crown-6 ether derivatives, 5 and 6 were synthesized from (R)-(-)-2-amino-1-bütanol. These chiral artificial receptors exhibit pronounced chiral recognition toward the enantiomers of
l- and d- amino acid derivatives. The highest enantioselectivity was observed in the case of Trp-OMe·HCl (KD/KL=12.5). |
| |
| Keywords: | amino acid chiral aza crown ether complexation molecular recognition |
| 本文献已被 SpringerLink 等数据库收录！ |
