The switch-on luminescence sensing of histidine-rich proteins in solution: a further application of a Cu2+ ligand |
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| Authors: | Wang Bin Gao Yang Li Hong-Wei Hu Zhi-Peng Wu Yuqing |
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| Affiliation: | State Key Laboratory of Supramolecular Structure and Materials, Jilin University, No. 2699, Qianjin Street, Changchun, 130012, China. |
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| Abstract: | A new probe/Cu(2+) complex for the detection of his-tagged protein has been developed, based on an improved probe, Dansyl-Gly-Py (1), by closely mimicing the structure of a peptide, ATCUN. In aqueous solution, 1/Cu(2+) has good selectivity to histidine and cysteine, and further can detect histidine-rich protein by releasing the quenched fluorescence of 1. |
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