Bioactives of Momordica charantia as Potential Anti-Diabetic/Hypoglycemic Agents |
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| Authors: | Bilin Xu Zhiliang Li Ting Zeng Jianfeng Zhan Shuzhen Wang Chi-Tang Ho Shiming Li |
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| Institution: | 1.College of Biology and Agricultural Resources, Huanggang Normal University, Huanggang 438000, China; (B.X.); (Z.L.); (J.Z.); (S.W.);2.College of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan 250355, China;3.Department of Food Science, Rutgers University, New Brunswick, NJ 08901, USA; |
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| Abstract: | Momordica charantia L., a member of the Curcubitaceae family, has traditionally been used as herbal medicine and as a vegetable. Functional ingredients of M. charantia play important roles in body health and human nutrition, which can be used directly or indirectly in treating or preventing hyperglycemia-related chronic diseases in humans. The hypoglycemic effects of M. charantia have been known for years. In this paper, the research progress of M. charantia phytobioactives and their hypoglycemic effects and related mechanisms, especially relating to diabetes mellitus, has been reviewed. Moreover, the clinical application of M. charantia in treating diabetes mellitus is also discussed, hoping to broaden the application of M. charantia as functional food. |
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| Keywords: | Momordica charantia bioactives hypoglycemic activity diabetes mellitus synergistic effect |
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