Enantio- and diastereo-controlled synthesis of (+)-juvabione employing organocatalytic desymmetrization and photoinduced fragmentation |
| |
| Authors: | Itagaki Noriaki Iwabuchi Yoshiharu |
| |
| Institution: | Graduate School of Pharmaceutical Sciences, Tohoku University, Aobayama, Sendai 980-8578, Japan. |
| |
| Abstract: | (+)-Juvabione, a natural sesquiterpene exhibiting insect juvenile hormone activity, has been synthesized from sigma-symmetric 4-(2-formyl-ethyl)cyclohexanone by employing organocatalytic asymmetric aldolization and Norrish I-type fragmentation as the key steps. |
| |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ |
|
