1. Department of Applied Chemistry, Faculty of Applied Science, Taibah University, Madinah, P.O. 3193, Saudi Arabia 2. Department of Chemistry, Faculty of Science, Northern Border University, P.O. 1321, Arar, Saudi Arabia
Abstract:
A series of 4-methylsulfanylpyrimidin-2(1H)-one peptide nucleic acid analogs were synthesized and tested for their antiviral activity against hepatitis B virus. Plaque reduction infectivity assay was used to determine the virus count reduction as a result of treatment with tested compounds.