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Cucurbit[8]uril induced heterodimerization of methylviologen and naphthalene functionalized proteins
Authors:Uhlenheuer Dana A  Young Jacqui F  Nguyen Hoang D  Scheepstra Marcel  Brunsveld Luc
Affiliation:Laboratory of Chemical Biology, Department of Biomedical Engineering, Technische Universiteit Eindhoven, Den Dolech 2, 5612 AZ Eindhoven, The Netherlands.
Abstract:Cucurbit[8]uril is a supramolecular inducer of protein heterodimerization for proteins appended with methylviologen and naphthalene host elements. Two sets of fluorescent protein pairs, which visualize the specific protein assembly process, enabled the interplay of the supramolecular elements with the proteins to be established.
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