直接进样–超高效液相色谱串联质谱法同时测定水源水中9种农药

建立直接进样–超高效液相色谱三重四级杆质谱联用(UPLC–MS–MS)快速测定水源水中9种痕量农药残留的方法。水样无需富集,经超高效液相色谱分离,串联三重四级杆质谱检测,在7.5 min内完成9种目标化合物的分析。9种农药的检出限(S/N≥3)在0.01~1.4μg/L之间,在各自的考察浓度范围内线性关系良好(r≥0.995)。在1.0~80μg/L添加水平内,实际样品的平均加标回收率为66.2%~114.0%,测定结果的相对标准偏差为2.3%~20.4%(n=6)。该法操作简便,重现性好,可用于饮用水源水中农药残留的快速测定。

Simultaneous Determination of 9 Pesticides in Water Samples by Ultra Performance Liquid Chromatography-Electrospray Tandem Mass Spectrometry with Direct Injection

A rapid analytical method for simultaneous determination of nine pesticides in water samples was developed by ultra performance liquid chromatography electrospray tandem mass spectrometry (UPLC-MS-MS) with direct injection. Nine target compounds were separated by using UPLC and detected by tandem MS in 7.5 minutes. The detection limits (S/N≥3) of 9 pesticides were in the range of 0.01-1.4 μg/L. All pesticides had good linear responses withr≥0.995. The average recoveries in the spiked levels of 1.0-80 μg/L ranged from 66.2% to 114.0% and the RSDs of determination results ranged from 2.3% to 20.4%(n=6). This method is simple and has good repeatability, it can be used for rapid determination of pesticide residues in drinking source water.