Synthesis and antiviral evaluation of 1,3-dimethyl-6-(1H-1,2,3-triazol-1-YL)pyrimidine-2,4(1H,3H)-dione derivatives |
| |
| Authors: | A Sh El-Etrawy A A-H Abdel-Rahman |
| |
| Institution: | (1) Department of Organic Chemistry, College of Pharmacy, Misr University for Science and Technology, 6th October City, Egypt;(2) Department of Chemistry, Faculty of Science, Menoufia University, Shebin El-Koam, Egypt; |
| |
| Abstract: | Some 6-(1H-1,2,3-triazol-1-yl)pyrimidine-2,4(1H,3H)-dione derivatives were synthesized via the reaction of 6-azido-1,3-dimethyluracil
with ethyl acetoacetate in the presence of sodium ethoxide. The antiviral activities of these compounds against Hepatitis
A virus (HAV, MBB-cell culture adapted strain) and Herpes simples virus type-1 (HSV-1) were tested. |
| |
| Keywords: | |
| 本文献已被 SpringerLink 等数据库收录！ |
|
