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Efficient microwave-assisted synthesis of 3-benzothiazolo and 3-benzothiazolino coumarin derivatives catalyzed by heteropoly acids
Authors:M. Khoobi  A. Ramazani  A. R. Foroumadi  H. Hamadi  Z. Hojjati  A. Shafiee
Affiliation:1. Chemistry Department, Zanjan University, P.O. Box 45195-313, Zanjan, Iran
2. Department of Medicinal Chemistry, Faculty of Pharmacy, and Pharmaceutical Sciences Research Center, Tehran, University of Medical Sciences, Tehran, 14176, Iran
3. Department of Chemistry, Chamran University, Ahvaz, 61357-4-3169, Iran
Abstract:Heteropoly acids are reported as efficient catalysts for the microwave-assisted synthesis of 3-benzothiazolo and 3-benzothiazolino coumarin from o-aminothiophenol derivatives with 3-acetly and 3-cyanochromen-2-one in good to excellent isolated yields (73?C95%). This study suggests new techniques for the synthesis of chromene derivatives using an inexpensive and easily available catalyst, a simple procedure, short reaction time, and good to excellent yields of the products.
Keywords:
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