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Fingerprint quality control of Angelica sinensis (Oliv.) Diels by high-performance liquid chromatography coupled with discriminant analysis
Authors:Shuai Wang  Hua-Qiao Ma  Ya-Jie Sun  Shi-Jun Shao
Affiliation:a Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000, PR China
b Graduate School of the Chinese Academy of Sciences, Beijing 100039, PR China
c Shenzhen Drug & Medical Apparatus Evaluation Center, Shenzhen 518034, PR China
Abstract:High-performance liquid chromatography (HPLC) was employed in the fingerprint analysis of Angelica sinensis (Oliv.) Diels. A chromatographic profile of A. sinensis (Oliv.) Diels from the Dingxi District of Gansu province, China, was established as the characteristic fingerprint. The feasibility and advantages of employing chromatographic fingerprint combined with discriminant analysis were investigated and demonstrated for the evaluation of A. sinensis (Oliv.) Diels for the first time. Our results showed that the chromatographic fingerprint combining with discriminant analysis can efficiently distinguish A. sinensis (Oliv.) Diels from various areas.
Keywords:Angelica sinensis (Oliv.) Diels   HPLC   Fingerprint   Discriminant
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