A study of the analytical behaviour of selected psycho-active drugs using liquid chromatography, ion trap mass spectrometry, gas chromatography and polarography and the construction of an appropriate database for drug characterisation |
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Authors: | Bernadette Doherty W. Franklin Smyth Venkataraman N. Ramachandran Catherine J. Hack Stephen McClean |
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Affiliation: | a School of Biomedical Science, University of Ulster, Coleraine BT52 1SA, Northern Ireland b School of Psychology, University of Ulster, Coleraine BT52 1SA, Northern Ireland |
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Abstract: | This paper provides analytical chemical information on a range of psycho-active drugs. This analytical chemical information on liquid chromatography-electrospray ionisation-mass spectrometry (HPLC-ESI-MS), ion trap mass spectrometry (ESI-MSn), gas chromatography-flame ionisation detection (GLC-FID) and polarographic behaviour is then incorporated into a database which is of use in drug characterisation. Application is found in the determination of selected drug compounds in hair samples. |
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Keywords: | Psycho-active drugs Ion trap mass spectrometry (ESI-MSn) Liquid chromatography-electrospray ionisation-mass spectrometry (HPLC-ESI-MS) Gas chromatography-flame ionisation detection (GLC-FID) Polarography Database |
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