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Electrochemical behavior of dopamine at a 3,3′-dithiodipropionic acid self-assembled monolayers |
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| Authors: | Lucia Codognoto Jonas AR Paschoal Murilo F Cabral Susanne Rath |
| Institution: | a Institute of Chemistry, Department of Analytical Chemistry, State University of Campinas, P.O. Box 6154, 13084-971 Campinas, SP, Brazil b Federal University of ABC, Rua Santa Adélia, 166, 09.210-170 Santo André, SP, Brazil c Institute of Chemistry of São Carlos, USP, Av. Trabalhador Sãocarlense 400, 13566-590 São Carlos, SP, Brazil |
| Abstract: | Monolayers of 3,3′-dithiodipropionic acid (DTDPA) were prepared on a polycrystalline gold electrode through a self-assembly procedure to produce a gold 3,3′-dithiodipropionic acid self-assembled monolayer (AuDTDPA) modified electrode. The characterization of the AuDTDPA electrode was investigated by cyclic voltammetry and ac impedance using the Fe(CN)6]3−/4− redox couple. The electrochemical behavior of DA on the modified electrode AuDTDPA was studied by cyclic and square-wave voltammetries, using phosphate buffer as supporting electrolyte. The oxidation peak current for DA increases linearly with concentration in the range of 0.35 × 10−5 to 3.4 × 10−5 mol L−1. The performance of the AuDTDPA modified electrode was evaluated for the electroanalytical determination of dopamine (DA) in a pharmaceutical formulation. The AuDTDPA modified electrode showed a stable behavior and the presence of surface-COOH groups avoided the passivation of the electrode surface during the dopamine oxidation. |
| Keywords: | Self-assembled monolayers 3 3&prime -Dithiodipropionic acid Dopamine Square-wave voltammetry Gold electrode |
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