| 植物内生真菌抗肿瘤活性成分研究进展 |
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| 引用本文： | 马养民,冯成亮. 植物内生真菌抗肿瘤活性成分研究进展[J]. 有机化学, 2008, 28(10): 1697-1706 |
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| 作者姓名： | 马养民 冯成亮 |
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| 作者单位： | 陕西科技大学化学与化工学院,西安,710021 |
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| 基金项目： | 国家自然科学基金，陕西科技大学校科研和教改项目 |
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| 摘 要： | 从植物内生真菌中获得了一系列具有多样性结构的抗肿瘤活性化合物. 对植物内生真菌所产生的萜类、生物碱、黄酮、甾体、酯类化合物的结构和对肿瘤细胞的抑制作用、抑制效果, 以及这些内生真菌的寄主植物等几方面进行了综述, 并且简要讨论了这些内生真菌与其寄主植物之间的化学生态学关系.
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| 关 键 词： | 植物内生真菌 代谢产物 抗肿瘤活性 |
| 收稿时间： | 2007-11-17 |
| 修稿时间： | 2008-01-12 |
Progress in the Studies on Antitumoral Natural Products from Endophytic Fungi |
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| MA,Yang-Min,FENG,Cheng-Liang. Progress in the Studies on Antitumoral Natural Products from Endophytic Fungi[J]. Chinese Journal of Organic Chemistry, 2008, 28(10): 1697-1706 |
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| Authors: | MA Yang-Min FENG Cheng-Liang |
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| Affiliation: | (College of Chemistry and Chemical Engineering, Shaanxi University of Science and Technology, Xi’an 710021) |
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| Abstract: | A number of antitumoral natural products have been isolated from endophytic fungi with diverse structures. Progress in various studies on antitumoral components is summarized, including the host plants of these endophytic fungi, the isolation and characterization of terpenoids, alkaloids, flavonoids, esters and steroids, and their inhibitory effects against tumor cells. In addition, the chemical ecology relationships between the endophytic fungi and their host plants are also briefly discussed. |
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| Keywords: | endophytic fungus metabolite antitumor |
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