| 高效液相色谱法研究黄连生物碱与吴茱萸黄酮配伍时成分含量的变化 |
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| 引用本文： | 潘浪胜,吕秀阳,许海丹,吴平东. 高效液相色谱法研究黄连生物碱与吴茱萸黄酮配伍时成分含量的变化[J]. 色谱, 2006, 24(2): 168-170 |
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| 作者姓名： | 潘浪胜 吕秀阳 许海丹 吴平东 |
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| 作者单位： | 1.Institute of Pharmaceutical Engineering, College of Materials Science and Chemical Engineering, Zhejiang University, Hangzhou 310027， China; 2.College of Chemical Engineering, Xiangtan University, Xiangtan 411105, China |
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| 基金项目： | 科技部科研项目;教育部优秀青年教师资助计划;广东省博士启动基金 |
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| 摘 要： | 为了研究中药配伍过程中是否发生化学反应,先从单味药材中提取不同的组分或大类化合物,然后对其进行配伍，用高效液相色谱法（HPLC）测定其在配伍前后的成分变化。实验采用HPLC对黄连生物碱与吴茱萸黄酮配伍后的各色谱峰进行检测和分析，结果表明黄连生物碱与吴茱萸黄酮配伍后色谱峰具有加和性,各成分的相对峰面积未见明显变化,且未见新的色谱峰产生，说明黄连生物碱与吴茱萸黄酮配伍后没有发生化学反应。
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| 关 键 词： | 高效液相色谱法 黄连生物碱 吴茱萸黄酮 中药配伍
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| 文章编号： | 1000-8713（2006）02-0168-03 |
| 收稿时间： | 2005-05-30 |
| 修稿时间： | 2005-05-30 |
Study on Content Variation of Chemical Constituents During Combination of Rhizoma Coptidis Alkaloids with Fructus Evodiae Flavonoids by High Performance Liquid Chromatography |
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| PAN Langsheng,L Xiuyang,XU Haidan,WU Pingdong. Study on Content Variation of Chemical Constituents During Combination of Rhizoma Coptidis Alkaloids with Fructus Evodiae Flavonoids by High Performance Liquid Chromatography[J]. Chinese journal of chromatography, 2006, 24(2): 168-170 |
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| Authors: | PAN Langsheng L Xiuyang XU Haidan WU Pingdong |
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| Affiliation: | 1.Institute of Pharmaceutical Engineering, College of Materials Science and Chemical Engineering, Zhejiang University, Hangzhou 310027， China; 2.College of Chemical Engineering, Xiangtan University, Xiangtan 411105, China |
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| Abstract: | In order to study the compatibility of Chinese herbal drugs,a method was proposed by investigating chemical reactions with combination of chemical constituents or major groups of chemical compounds of Chinese herbal drugs.The content variation of chemical constituents during combination of rhizoma coptidis alkaloids with fructus evodiae flavonoids was analyzed by high performance liquid chromatography(HPLC).The experimental results showed that only small changes of the relative peak areas of different chemical constituents were observed and no new peaks were detected.No chemical reactions were observed during the compatibility test of rhizoma coptidis alkaloids with fructus evodiae flavonoids. |
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| Keywords: | high performance liquid chromatography(HPLC) rhizoma coptidis alkaloids fructus evodiae flavonoids compatibility of Chinese herbal drugs |
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