Piezoelectric immuno sensor for the detection of candida albicans microbes |
| |
| Authors: | H Muramatsu K Kajiwara E Tamiya I Karube |
| |
| Institution: | Seiko Instruments Inc., Research and Development Dept., Takatsuka-shinden, Matsudo-shi, Chiba 271 Japan;Research Laboratory of Resources Utilization, Tokyo Institute of Technology, Nagatsuta-cho, Midori-ku, Yokohama 227 Japan |
| |
| Abstract: | The system consists of an AT-cut quartz piezoelectric crystal, oscillator and frequency counter. The surface of the palladium-plated electrodes is oxidized anodically, and anti-Candida antibody is immobilized onto the surface. The crystal sensor is dipped into Candida suspension and the surface mass increase, caused by immuno-adsorption of Candida, is measured by the decrease in the resonant frequency of the crystal. The frequency shift is correlated with C. albicans concentrations in the range 106?5 × 108 cells cm?3. The crystal sensor showed no response to Saccharomyces cerevisiae. |
| |
| Keywords: | |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
