Domain formation in lipid bilayers probed by two-dimensional infrared spectroscopy |
| |
| Authors: | Volkov Victor V Chelli Riccardo Righini Roberto |
| |
| Affiliation: | European Laboratory for Nonlinear Spectroscopy (LENS), Via Nello Carrara 1, I-50019 Sesto Fiorentino, Italy. v.volkov@lens.unifi.it |
| |
| Abstract: | Two-dimensional infrared (2D-IR) spectroscopy has been used to probe structure and dynamics in binary sphingomyelin/phospholipid liposomes. The liposomes consist of 1-palmitoyl-2-linoleyl phosphatidylcholine (PLPC) and sphingomyelin (SPM) in the ratio 1:1. The diagonal part of the 2D-IR spectra shows two bands which are due to amide I of SPM and to the carbonyl moieties of PLPC. The diagonal components of the 2D-IR spectra reveal a difference in the molecular dynamics. The presence of off-diagonal cross-peaks indicates the occurrence of intermolecular structural correlation. The intensity of the cross-peaks is consistent with segregation of two lipid components into PLPC and SPM molecular domains. |
| |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ |
