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生物力学与基因-献给周培源教授诞辰100周年
引用本文:冯元桢.生物力学与基因-献给周培源教授诞辰100周年[J].力学进展,2002,32(4):484-494.
作者姓名:冯元桢
作者单位:美国California大学San
摘    要:生物界包罗万象,其中有力的作用,所以有生物力学.自Galileo,Harvey, Boreli, Hooke, Euler,Young等创始以来,生物力学阐明了鸟飞鱼游,人体运动,血液循环,人工脏器等,对人世社会,有所贡献.生物力学的基础是质点力学,传统地用连续体力学的概念来简化.但近年做生物组织在应力的作用下改造的问题,引起了必须更改传统连续体力学的几个公理的问题.我们将仔细讨论这些公理,然后指出新公理存在的理由,是由于基因在细胞里的日常工作.基因不单主宰遗传,变异;并且忙着控制日常生活.不过,现在仅见其端倪.详细的情形,要等将来来阐发了. 

关 键 词:连续体力学公理    生物力学公理    组织改造    物性改造    无应力状态改造    公理改造    改造由于基因    基因力学
修稿时间:2002年6月24日

BIOMECHANICS AND GENE ACTIVITIES --CELEBRATING THE CENTENNIAL OF PROFESSOR CHOU PEIYUAN
Fung Yuancheng.BIOMECHANICS AND GENE ACTIVITIES --CELEBRATING THE CENTENNIAL OF PROFESSOR CHOU PEIYUAN[J].Advances in Mechanics,2002,32(4):484-494.
Authors:Fung Yuancheng
Institution:Department of Bioengineering, University of California, LaJolla, CA 92903-412, USA
Abstract:All biological phenomena involving force and motion are in the realm of biomechanics. Mechanics people, from Galileo on to today, have used the principles of conservation of mass, momentum, and energy to make contributions to human well being. They have added to the scientific understanding of locomotion, circulation, respiration, renal and nervous functions, and artificial internal organs. In recent years, many people, working on tissue engineering, arteriosclerosis, and other health problems, have to focus on the problem of finding out how do living tissues change or remodel themselves under stress. They found that some of the classical conservation laws do not apply, and there is a problem of introducing new axioms to biomechanics. The purpose of the present paper is to discuss these new axioms, then go on to point out that the basic reason for these new axioms is the activity of the genes in our cells. Some of our genes work daily to control our lives. Their functions are not limited to genetics and mutation. This points to a new lead to new thoughts. A new science is waiting to be developed.
Keywords:Axioms of continuum mechanics  Axioms of biomechanics  Tissue remodeling  Me-chanical properties remodeling  Zero-stress state remodeling  Axioms remodeling  Remodeling due to gene action  Gene mechanics  
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