Chromatographic Behaviour and Lipophilicity of Estradiol Derivatives |
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| Authors: | M M Acanski |
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| Institution: | 1. Department of Applied and Engineering Chemistry, Faculty of Technology, University of Novi Sad, Bulevar cara Lazara 1, 21000, Novi Sad, Serbia and Montenegro
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| Abstract: | The retention behaviour of estradiol derivatives has been studied by HPLC on polar chemically bonded stationary phases: C3CN, DIOL and C3NH2, commercially available columns. The mobile phases used were: methanol-water and acetonitrile-water in various proportions. Reversed-phase chromatography occurred on polar chemically bonded stationary phases. Correlation between the retention constants of estradiol derivatives obtained on polar chemically bonded phases and log P calculated via different methods was examined too. |
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