Highly biocompatible, hollow coordination polymer nanoparticles as cisplatin carriers for efficient intracellular drug delivery |
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| Authors: | Lian Hong-Yuan Hu Ming Liu Chia-Hung Yamauchi Yusuke Wu Kevin C-W |
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| Institution: | Department of Chemical Engineering, National Taiwan University, No. 1, Sec. 4, Roosevelt Road, Taipei 10617, Taiwan. |
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| Abstract: | Highly biocompatible coordination polymer (Prussian Blue) nanoparticles (LC(50) > 1000 μg mL(-1)) with a hollow interior and a microporous framework (denoted as HPB) are utilized as an anticancer drug (i.e. cisplatin) capsule for chemotherapy of bladder cancer T24 cells. |
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