Simple chiral sulfonamide primary amine catalysed highly enantioselective Michael addition of malonates to enones |
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| Authors: | Luo Chunhua Jin Yu Du Da-Ming |
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| Affiliation: | School of Chemical Engineering and Environment, Beijing Institute of Technology, Beijing 100081, People's Republic of China. |
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| Abstract: | A chiral sulfonamide primary amine-organocatalysed, highly enantioselective Michael addition of malonates to enones has been developed. This reaction afforded the corresponding products in excellent yields (up to 99%) and excellent enantioselectivity (up to 99% ee). |
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