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Synthesis and structure of new 3,7,10-substituted-phenothiazine derivatives
Authors:Raluca Turdean  Elena Bogdan  Anamaria Terec  Anca Petran  Laurian Vlase  Ioan Turcu  Ion Grosu
Institution:(1) Organic Chemistry Department and CCOCCAN, “Babes-Bolyai” University, RO-400028 Cluj-Napoca, Romania;(2) Faculty of Pharmacy, University of Medicine and Pharmacy “Iuliu Hațieganu”, RO-400023 Cluj-Napoca, Romania;(3) National Institute of Research and Development for Isotopic and Molecular Technologies, RO-400293 Cluj-Napoca, Romania
Abstract:The synthesis of new 3,7-dibromophenothiazine derivatives bearing bromoalkyl, mercaptoalkyl and alkylthioacetate groups on the N atom at position 10 is reported. The Suzuki coupling reaction of one of these derivatives via the bromine atoms at positions 3 and 7 with bromothiophene derivatives is also discussed. MediaObjects/11532_2008_88_Fig1_HTML.jpg
Keywords:N-Bromoalkyl  N-alkythioacetate and N-Mercaptoalkyl 3  7-dibromophenothiazines  Podands  Suzuki coupling
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